Information About Sunitinib Malate Capsules
Sunitinib Malate Capsules is a tyrosine inhibitor and indolinone mimic with latent anticancer potential. These Capsules inhibits angiogenesis and cell proliferation by blocking the activity of vascular endothelial kinase 2 (VEGFR2), platelets-producing growth factor b (PDGFRb), and c-kit receptors. These mediators also block tyrosine kinase 3 linked with Fms (FLT3), a tyrosine kinase receptor created by certain leukaemia cells, from being phosphorylated.
In the United States, Sunitinib Malate Capsules was first certified in 2006. It has been manufactured and used in India since the US patent expired.
Uses of Sunitinib Malate
- Kidney Cancer
- Gastrointestinal Stromal Tumour
Benefits of Sunitinib Malate (Sutekast)
In Kidney Cancer
Sunitinib Malate (Sutekast) is a cancer-fighting medicine. Sunitinib capsule acts by attaching and inhibiting a specific cell surface protein (tyrosine kinase) that promotes tumor growth. It also prevents the tumor from forming new blood vessels. That’s how it prevents dangerous tumors from growing.
In Gastrointestinal Stromal Tumours
GISTs (gastrointestinal stromal tumours) are tumours of the gut. The unique cells in the gut wall begin to proliferate uncontrollably. Malignant tumours (tumours that spread to other parts of the body) and benign tumours (tumours that do not spread to other parts of the body) are both possible (don’t spread to other parts of the body). Sunitinib capsule is an anti-cancer medication. Sunitinib capsule inhibits tumour growth by binding to and blocking a specific cell surface protein (tyrosine kinase). It also inhibits the tumor’s ability to produce new blood vessels. This is how deadly cancers are prevented from forming.
Side effects of Sunitinib Malate
- Weakness in the muscles
- Edema (swelling)
- Swelling (edema) in the hands and legs
- Abdominal pain
- Discoloration of skin
- Dry skin
- High blood pressure
- Painful blisters on hands and feet
- Stomatitis (Inflammation of the mouth)
- Hair discoloration
- Pain in extremities
- Back pain
- Joint pain
- Taste change
How to use Sunitinib Malate
Take Sunitinib Capsules as prescribed by your doctor in the dosage and time frame specified. Take it all in at once. Avoid chewing, crushing or breaking it in any way. With or without meal, it is best to take Sunitinib capsule at the same time each day.
How Sunitinib Malate Capsules Works
Sunitinib capsule is a cancer-fighting drug. It works by boosting the immune system, which then targets cancer cells indirectly. It stops the tumour from sprouting new blood vessels. It also inhibits the synthesis of chemical messengers (cytokines and growth factors) that promote cancer cell proliferation. This is how cancer is combated.
Packing of Sutekast 25mg
Alcohol (SEEK THE ADVICE OF YOUR DOCTOR)
Pregnancy (SEEK THE ADVICE OF YOUR DOCTOR)
Breast-feeding (SEEK THE ADVICE OF YOUR DOCTOR)
Kidney (SAFE IF PRESCRIBED)
Q. Is it safe to take Sunitinib Malate (Sutekast) on an empty stomach?
It is possible to take? this medicine with or without food. Always follow your doctor’s instructions to the letter. The Capsules should not be crushed, sliced, or chewed. With water, swallow it whole. On the scheduled days, you should take Sunitinib Malate (Sutekast) at nearly the same time.
Q. What are the side effects of Sunitinib Malate?
This medicine has a low incidence of adverse effects and is assessed in a controlled manner.
Diarrhea, nausea, exhaustion, skin yellowing, elevated blood pressure, stomatitis, and skin responses on the hands and feet are the most prevalent side effects of this medicine therapy. Asthenia, change in taste, constipation, skin discoloration, diarrhoea, stomatitis, and anorexia are common side effects in Phase III placebo-controlled GIST investigations. These are all possible symptoms. If any of these symptoms are severe or do not go away, contact your doctor.
Q. Will I need any blood tests while taking Sunitinib (Sutekast)?
While taking Sunitinib (Sutekast), your health care provider will check on you on a frequent basis to monitor side effects and assess your response to medication. Blood pressure testing is one example, but it is not the only one.
Q. Is it necessary for me to take birth control while taking Sunitinib 25 (Sutekast)?
During your treatment, including when your doctor recommends you to temporarily stop taking this medicine and for 4 weeks following your final dosage, continue to use contraception. While on therapy, this medicine may enter into the sperm of men. As a result, even if they have had a vasectomy, males must always use a latex condom whenever they have sexual contact (surgery that prevents a man from causing a pregnancy). Use the contraception while taking Sunitinib 25 (Sutekast), during any treatment breaks, and for four weeks following the last dosage.